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old imageThe Bioexpression and Fermentation Facility (BFF) is a large fermentation pilot plant located in Athens, GA at the University of Georgia. Established in 1967, the BFF is one of the largest facilities of its kind in the Southeast. It consists of four divisions, including the Fermentation Research Facility (FRF), the Protein Purification Facility (PPF), the Cell Culture Facility (CCF), and the Monoclonal Antibody Facility (MAF). The BFF provides clients with a comprehensive range of biomanufacturing services across a wide range of areas, such as fermented foods, recombinant proteins, monoclonal antibodies, cosmetics precursors, vaccines, biofuels, and biomedical products. 


The BFF has 23 bioreactors ranging from 1 L to 750 L, with centrifugation and tangential flow filtration capabilities for all reactor sizes. The facility also has 2 HPLCs with a flow rate between 1 mL/min to 800 mL/min, and processing capabilities at temperatures from 4 ˚C to 80 ˚C. With 10 staff members, the BFF has years of experience in fermentation and protein purification. In addition to serving several in-state biotech companies and academic researchers, the BFF has provided services to clients in over 37 states and six countries. 


The BFF has a solid international reputation for providing fermentation and protein purification services. Significant equipment upgrades have been funded by income from service work and government grants over the past decade to ensure the facility can continue to grow in the future. Overall, the BFF is an excellent choice for anyone looking for comprehensive biomanufacturing services from an experienced and trusted facility.